Scientist on Computer

Postdoctoral Fellowship Awardees
2021 - 2022

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Jungmin Lee, PhD

UNIVERSITY OF CALIFORNIA SAN FRANCISCO

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Kiyoshi Saeki, MD PhD

COLUMBIA UNIVERSITY IRVING MEDICAL CENTER

Know more about Jungmin Lee, PhD


Jungmin Lee, PhD is a postdoctoral fellow in the laboratory of Dr. Wendell Lim at the University of California, San Francisco. Dr. Lee received her BS in Chemistry from Duke University and her PhD in Chemistry from Harvard University. She is interested in rationally engineering biological molecules to precisely control their behaviors and using these engineering principles to inform better therapeutic designs. Her PhD research in the laboratory of Dr. Pamela Silver focused on designing novel protein therapeutics with greater tissue specificity and reduced off-target cross-reactivity based on protein structure-function relationships and spatial geometry of target proteins. Now, Dr. Lee wants to expand her expertise to the cellular level and engineer cells that can perform novel therapeutic functions in response to various input signals at the site of the disease. She is currently developing a smarter, next-generation chimeric antigen receptor (CAR) T cell therapy by incorporating synthetic gene circuits that can improve tumor recognition and tumor infiltration of CAR T cells for the treatment of pancreatic ductal adenocarcinoma. Linkedin Lab Website




Know more about Kiyoshi Saeki, MD PhD


Dr. Kiyoshi Saeki is a physician-scientist. He received his M.D. from the Nagasaki University, Nagasaki, Japan, in 2009 and his Ph.D. from the Kyushu University, Fukuoka, Japan, in 2019. He started studying pancreatic cancer as a graduate student in 2015, where he discovered that concomitant IPMN in PDAC is an independent predictive factor for the development of new PDAC in remnant pancreas. He also investigated ITPN (intraductal tubulopapillary neoplasm) which is also a pancreatic precancerous lesion, and found that recurrence is possible even for a primary noninvasive ITPN. These findings clarified some of the outstanding questions regarding the pathological features of IPMN and ITPN. As a GI surgeon, he recognizes the needs to improve the care and management of patients with IPMN. Hence, he joined Dr. Gloria Su’s lab in 2019 to study the underlying mechanism of how precursor lesions progress to pancreatic cancer using GEMMs (genetically-engineered mouse models) and 3D organoids generated from murine and human IPMN, applying his prior experiences in cancer biology and pathology of pancreatic cancer. He is grateful to the RLFCRF fellowship for supporting his research in IPMN and PDAC. Linkedin Lab Website